Sunday, 12 October 2025

Empty-amnion sign

Definition

The Empty-amnion sign refers to sonographic visualization of an amnion (an amniotic membrane/cavity) in the gestational sac without a concomitant identifiable embryo/embryonic pole when one would be expected by gestational age and by scanning plane. It has been described as a strong predictor of early pregnancy failure in multiple series and can help confirm nonviability when present.

Images

Ultrasound Report - line

Example: "Intrauterine gestational sac with visible amnion. No embryo/embryonic pole identified consistent with empty-amnion sign."

Conclusion

Visualization of an amnion without an identifiable embryo (empty-amnion sign) is strongly suggestive of early pregnancy failure in the appropriate clinical context.

Enter CGA to override LMP-derived GA.
Tick if structure is visualized on scan
Empty-amnion assessment
Amnion vs embryo presence and MSD/CRL interpretation
Ready
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Bilingual Quiz — Empty Amnion Sign (EN / HI)





  

    
Empty Amnion Sign — Sonography — Quiz

    
Empty Amnion संकेत — सोनोग्राफी — क्विज़

    
10 MCQs — choose the best answer (A–D)

    
  

  

    
    
  









  
  
  
  
  





Created: Empty Amnion Sign MCQ — bilingual (EN/HI)
















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